Multidrug-resistant tuberculosis in north-west of Iran and Republic of Azerbaijan: a major public health concern for Iranian people.

نویسندگان

  • Jalil Rashedi
  • Behroz Mahdavi Poor
  • Abdolnasser Rafi
  • Mohammad Asgharzadeh
  • Jalal Abdolalizadeh
  • Seyyed Reza Moaddab
چکیده

BACKGROUND Republic of Azerbaijan is considered as an area with high prevalence of multi-drug resistant tuberculosis. Uncontrolled travelling of Azerbaijanis people to Iran is the issue that needs to be considered as an important issue. METHODS This study was conducted on 32 patients with tuberculosis from Baku-Nakhchivan and 48 patients from Iran during 2012 to 2014. Colonies of Mycobacterium tuberculosis were examined after isolating them from patients using proportional method on Lowenstein-Jensen media regarding resistance encounter with Rifampin, Isoniazid and Ethambutol. RESULTS Among M. tuberculosis isolates belonging to 32 foreign patients; 69%, 72% and 56% of them were resistant to Rifampin, Isoniazid and Ethambutol, respectively (multidrug resistance tuberculosis: MDR-TB: 62.5%). From 48 isolates of Iranian patients; 8%, 4% and 4% were resistant to Rifampin, Isoniazid and Ethambutol, respectively (MDR-TB: 2.1%). CONCLUSIONS Resistant strains are common in Baku-Nakhchivan's people. To prevent the transmission of these strains to Iranians, strategies such as; establishing a medical campus in border lines of both countries for clinical examinations and conducting screening tests regarding tuberculosis infection in applicants for entering Iran must be taken in to account.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Multidrug-Resistant TB as A Major Concern for Tuberculosis Control Programs

1. Dept. of Epidemiology & Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran 2. Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, Iran 3. Dept. of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 4. Dept. of Epidemiology & Biostatistics, School of Publi...

متن کامل

Role of Treatment Cost on Transmission of Multidrug-Resistant Tuberculosis Into Iran.

TO THE EDITOR—Treatment of multidrugresistant (MDR) tuberculosis requires longtime usage of toxic drugs that are unpleasant for patients and costly for patients and governments. The costs in terms of human suffering, disability, and socioeconomic loss are immeasurable. In Iran, diagnosis and treatment of the disease are offered free of charge; fees are paid by the government and several chariti...

متن کامل

The 10-year Trend of TB Rate in West Azerbaijan Province, Iran from 2001 to 2010

BACKGROUND The present study aimed to explore some risk factors affected the mean of the number of tuberculosis (TB) in West Azerbaijan Province, Iran between 2001 and 2010. METHODS Our time series study analyzed the data of 2,560 TB patients as registered with TB Patients Care System in West Azerbaijan Province from early 2001 to 2010. A checklist was prepared for collecting the data and the...

متن کامل

Differential protein expression in Mycobacterium tuberculosis susceptible and multidrug resistant isolates

Introduction: Infections by multidrug resistant Mycobacterium tuberculosis (MDR-TB) is a major public health challenge. Secretion of proteins by M. tuberculosis plays an important role in the pathogenesis of the bacterium. We compared the protein profiles of susceptible M. tuberculosis and MDR-TB isolates using proteomic analyses, namely two dimensional gel electrophoresis (2DE) and mass spectr...

متن کامل

A STUDY OF MYCOBACTERIUM TUBERCULOSIS DRUG RESISTANCE IN PULMONARY TUBERCULOSIS

Tuberculosis remains a major public health problem in both developing and developed countries. Drug-resistant tuberculosis is an increasing health problem and serious challenge to tuberculosis (TB) control programs. Information about the susceptibility pattern of Mycobacterium tuberculosis isolates against anti-tuberculosis drugs is an important aspect to TB control. The objectives of the s...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of research in health sciences

دوره 15 2  شماره 

صفحات  -

تاریخ انتشار 2015